Cell behaviour towards different wettable biomaterials surfaces: Functional role of integrins in intracellular signalling processes

General Information

This interdisciplinary project covers a wide range from material sciences to cell biology and aims at a better understanding of the tissue compatibility of biomaterials. Existing knowledge on the activity of integrins on biomaterials available at Helmholtz-Zentrum Geesthacht will be combined with the knowledge and expertise in intracellular signalling processes, particularly on cAMP, which will be brought into the project by the M.-C. fellow, Dr Nathalie Faucheux. A particular focus is on how adsorption of adhesive proteins like vitronectin, fibronectin, and others on well defined surfaces such as self assembling monolayers interact with integrins and influence intracellular signalling pathways. Results will be used in biohybrid organ technology and tissue engineering.

EU-Programme Acronym and Subprogramme Area	FP5-HUMAN POTENTIAL-2000, Marie-Curie Individual Fellowship
Project Type	Marie-Curie Individual Fellowship
Contract Number	HPMF-CT-2000-00883
Co-ordinator	Helmholtz-Zentrum Geesthacht (D)

Total Eligible Costs (€)	HZG Eligible Costs (€)	EC Funding for HZG (€)
147.150	147.150

Contact Person at HZG

Univ.-Prof. Dr. sc. nat. Andreas Lendlein, Institute of Biomaterial Science, Phone: +49 3328-352-450, (initial contact: Dr. Thomas Groth, Institute of Polymer Research) E-mail contact

Participants

Université de Technologie de Compiègne (FR)

Last Update: 23. September 2020