Institute of Materials Research
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Metallic Biomaterials

The “Metallic Biomaterials” division examines and develops new implant materials based on titanium and magnesium.

Magnesium provides optimal properties for use as an absorbable implant material in medical applications such as orthopaedics, traumatology and paediatrics.

Magnesium possesses characteristics similar to bone, is an essential element required by the human body and likely stimulates new bone formation. In order to establish magnesium as a marketable implant material, an array of factors must be examined: the properties of the base material must be considered among other factors in regards to the mechanical characteristics and degradation behaviour. It is equally important to understand what impact the material exerts on the cells that grow on its surface and ultimately on the organism. Furthermore, researchers must ensure that the steps in processing, from the base material to implant prototypes, do not cause significant property alterations.

The Magnesium Innovation Center (MagIC) supplies the base material: the magnesium alloy. The “Metallic Biomaterials” division examines factors that lead to magnesium degradation under physiological conditions. The scientists also test magnesium alloy properties in the cell culture. In cooperation with MagIC, the processing of the material is optimised.

Contact

Research Networks:

Helmholtz Virtual Institute MetBioMat

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Virtual Institute MetBioMat

RÅC - SynchroLoad

Synchroload Kp

push out testing of a mini screw (Mg-alloy) in bone tissue

SynchroLoad - Failure in biodegradable metal implants

A Swedish-German research collaboration in the fields of materials science and structural biology (Röntgen-Ångström-Cluster).

In this project, we aim to understand how implant degradation and failure mechanisms work for a biodegradable Mg implant where corrosion processes and (bio)chemistry form a complex network of interactions in the living system. The tissue-to-implant interface will be fully characterized biomechanically, morphologically, biologically and chemically. Finally, a comparison of the bone structure around different implant materials will be performed.

Röntgen-Ångström-Cluster

MgBone

MgBone graphical abstract

MgBone - Multimodal imaging for structural analysis of bone modeling induced by degraded magnesium implants

Cooperation in the context of the funding sheme research on condensed matter on large devices. There are three partners: The Molecular Imaging North Competence Ceter (MOIN CC) in Kiel, the Helmholtz Center Geesthacht (HZG) and the Department of Prosthodontics of the University of Malmö (MAH)

Together, a measurement and evaluation environment and a network of competences are to be created, with the help of which the biomechanical, biomedical, biochemical and physical suitability of innovative implants can be evaluated.

Graduate School M4B - Materials for brain

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Materials for Brain: Thin film functional materials for minimally invasive therapy of brain diseases

Cooperation between the Christian-Albrechts-University of Kiel (CAU), the University Clinic of Schleswig-Holstein (UKSH) and the Helmholtz Center-Geesthacht (HZG).

Within the framework of the Graduate School, minimally invasive treatment strategies for diseases of the brain based on novel thin-film material compounds are to be explored in a complexity and functionality that goes far beyond previous approaches. The realisation of such treatment strategies in clinical medicine will be a milestone in the therapy of these diseases.

The development of such cutting-edge localized therapies and suitable functional materials requires substantial collaboration between materials science and medicine, as well as new approaches to solutions and creative openness to the view of the respective other subject.