Most cited article

The article Annika Jahnke, Lutz Ahrens, Ralf Ebinghaus, Urs Berger, J.L.Barber und C. Temme: "An improved method for the analysis of volatile polyluorinated alkyl substances in environmental air samples", published in Analytical and Bioanalytical Chemistry is being featured on the ACS Publications website as one of the Most-Cited Articles published in 2007.

This article describes the optimisation and validation of an analytical method for the determination of volatile polyfluorinated alkyl substances (PFAS) in environmental air samples. Airborne fluorinated telomer alcohols (FTOHs) as well as fluorinated sulfonamides and sulfonamidoethanols (FOSAs/FOSEs) were enriched on glass-fibre filters (GFFs), polyurethane foams (PUFs) and XAD-2 resin by means of high-volume air samplers. Sensitive and selective determination was performed using gas chromatography/chemical ionisation–mass spectrometry (GC/CI–MS). Five mass-labelled internal standard (IS) compounds were applied to ensure the accuracy of the analytical results. No major blank problems were encountered. Recovery experiments were performed, showing losses of the most volatile compounds during extraction and extract concentration as well as strong signal enhancement for FOSEs due to matrix effects. Breakthrough experiments revealed losses of the most volatile FTOHs during sampling, while FOSAs/FOSEs were quantitatively retained. Both analyte losses and matrix effects could be remediated by application of adequate mass-labelled IS. Method quantification limits (MQLs) of the optimised method ranged from 0.2 to 2.5 pg/m3 for individual target compounds. As part of the method validation, an interlaboratory comparison of instrumental quantification methods was conducted. The applicability of the method was demonstrated by means of environmental air samples from an urban and a rural location in Northern Germany.


Prof. Dr. Ralf Ebinghaus
Department for Environmental Chemistry
Institute for Coastal Research
GKSS Research Centre Geesthacht
Max-Planck-Str. 1
21502 Geesthacht

Tel. +49 (0)4152 87 2354
mobile +49 (0)170438 4422
e-mail: ralf.ebinghaus[at]