Institute of Biomaterial Science


Editor´s Choice

Polydepsipeptide Block Stabilized Polyplexes For Efficient Transfection of Primary Human Cells

Degradable block copolymers have shown great potential to combine transfection capability with low toxicity of the transfection agent. Depsipeptide blocks exhibiting strong physical interactions were conjugated with PEI moieties to di and triblock copolymers. Upon nanoparticle formation and complexation with DNA, the resulting polyplexes (sizes typically 60-150 nm) showed remarkable stability compared to PEIonly or lipoplex, and facilitated efficient gene delivery. These nanocarriers form the basis for a delivery platform-technology especially for gene transfer to primary human cells. more


Non-continuously Responding Polymeric Actuators

Current polymeric actuators move because of their continuous response to the input signals of the controlling unit and cannot be interrupted without stopping or eliminating the input trigger. The new type of non-continuously responding actuator materials are capable of pausing their movements in a defined manner upon continuous cyclic heating and cooling. more

TdoT Teltow 2014_2

Hands-on Science

Approximately 500 visitors attended the Open House at the Institute of Biomaterial Science in Teltow this past Saturday. Several stations on campus welcomed participation. more


Expansion of Biomaterial Sciences in Teltow: New Construction of the Biomedical Technology Centre III

The Institute of Biomaterial Science of the Helmholtz-Zentrum Geesthacht in Teltow will hold its groundbreaking ceremony for the construction of the new Biomedical Technology Centre III on June 13th, 2014. The event marks the third phase of construction at the Teltow research campus and will be attended by Brandenburg’s Research Secretary Dr. Sabine Kunst and by Chairman of the Board at the Helmholtz-Zentrum Geesthacht, Assistant Secretary Wilfried Kraus. more


Opening Event of the Helmholtz Graduate School

On Friday September 27th the opening event of the Helmholtz Graduate School for Macromolecular Bioscience will take place at the Free University of Berlin. Following welcoming words from the Scientific Director of the Helmholtz-Zentrum Geesthacht Prof. Dr. Wolfgang Kaysser and greetings from politics and science, the participants will get a brief introduction of the scientific work. more

Abb. 1: In dem Modell einer Fensterjalousie werden die Temperatur-Gedächtnis Polymer-Aktuatoren zum temperaturabhängigen Öffnen und Schließen der Lamellen genutzt. Der Temperaturbereich, in dem sich die Lamellen der Jalousie bewegen, ist programmierbar. Diese Fähigkeit wird als Temperatur-Gedächtnis bezeichnet.

First shape-memory plastics able to reverse deformation

Biomaterial researchers in Teltow have developed plastics that can repeatedly change from one shape to another and then back again when temperatures fluctuate within a selected range. The material, dubbed “polymer actuators” by its creators, thus overcomes a major limitation that affects similar materials. Up until now, polymers with temperature-controlled shape memory could only change form once. more

Eröffnung: Biomedizintechnikum II am Standort Teltow

Am 12. Dezember 2011 um 18 Uhr wird das neue Forschungsgebäude des Zentrums für Biomaterialentwicklung des Helmholtz-Zentrums Geesthacht seiner Bestimmung übergeben. Mit rund 2000 Quadratmetern Nutzfläche bietet der Erweiterungsbau Raum für neue Laboratorien und Büros. Um die Entwicklung neuartiger, kunststoff-basierter Materialien voranzubringen, werden hier insbesondere Sterilisationstechniken, neuartige Wirkstoff-Materialkombinationen und der Aufbau von Makromolekül-Bibliotheken Gegenstand der Forschung sein.

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