Biointerface Engineering

Methods

General Techniques


  • Cell culture and appropriate analysis techniques for regio specific cytotoxicitity and compatibility screenings in vitro/ in vivo
  • Biofunctionality tests
  • Animal model studies in cooperation with Charité, Universitätsmedizin Berlin/ Berlin-Brandenburg Centre for Regenerative Therapies (BCRT)/ Helmholtz-Zentrum Rossendorf, Technische Universität Dresden
  • Tissue Engineering

Methods


  • Cytotoxicity testing of polymer based biomaterials according to the DIN ISO 10993 (direct, indirect)
  • Hemocompatibility testing of polymer based biomaterials according to the DIN ISO 10993 (static/dynamic)
  • Protein adsorption studies
  • 2D cell culture in static and dynamic systems
  • FACS and MACS
  • Confocal laser scanning microscopy
  • Time laps microscopy
  • Laser dissection and catapulting unit
  • Permeability testing (permeability and binding strength of the polymer-tissue-connection)
  • Shear stress resistance testing
  • Hen's Egg Test on the Chorioallantoic Membrane (HET-CAM)
  • In vivo testing
  • Intravital microscopy
  • Tissue oxygen tension microcatheter
  • Oxygen saturation measurement system
  • Laser doppler system
  • Histology including resin embedding