PhD position (m/f)
|Beginn der Ausschreibung||20.07.2018|
|Ende der Ausschreibung||16.08.2018|
|Institut||Institut für Werkstoffforschung|
The Helmholtz Zentrum Geesthacht (HZG) is one of the leading developers of magnesium - based implants for various applications, e.g. orthopedics and cardiovascular, with the goal to promote the healing of the tissue. The research centre hosts the studies of the development of magnesium - based implants which consists of improving the mechanical and degradation performance of the metal, characterisation, processing and in vitro biological testing of the newly developed implant materials. This research is extended to in vivo performance studies at the outstation of HZG, Molecular Imaging North Competent Centre (MOIN CC) in Kiel (http://www.moincc.de).
We are seeking to fill a position on the topic ‘Evaluation of influence of magnesium alloys on macrophage polarisation using multimodal imaging’’ at our outstation, MOINCC in Kiel. We therefore invite applications for a PhD (m/f) position. The position is initially limited to 3 years, starting date as soon as possible. The place of employment is Kiel, Helmholtz-Zentrum Geesthacht outstation at Molecular Imaging North Competence Center (MOIN CC).
The focus of the project is to develop the in vivo strategies to track macrophages in a bone-fracture model using multimodal imaging and to identify the role of macrophages in bone healing process using immunohistochemistry and histology.
You will be responsible for:
- developing approaches for in vivo immune cell tracking such as macrophages in presence of Mg as an implant by optical imaging
- establishing a timeline - migration, distribution and fate of macrophages at the site of inflammation in vivo by optical imaging
- identifying the macrophage phenotype modulating the inflammation and bone healing process by FACS and multi-photon microscopy
- the biological characterisation of tissue-to-implant interface by histology, immunohistochemistry and molecular imaging
This position requires a Master’s degree in natural sciences (preferably biology, biochemistry or cell biology) or equivalent qualification. We ask for a theoretical background on inflammation, preferably with knowledge on macrophage polarisation. The position requires strong analytical skills and proven experience in at least one of the following techniques: immunohistochemistry, multi-photon microscopy, confocal microscopy, optical imaging and FACS. Initial experience in in vivo experiments is desirable. You should exhibit team spirit, excellent communication and organization skills as well as a sound expertise of English language.
- multinational work environment with over 900 colleagues from more than 50 nations
- extensive options of vocational training (i. a. expert seminars, language courses or leadership seminars)
- flexible working hours and various models to ensure the compatibility of family and career
- excellent infrastructure including modern work spaces
- remuneration according to the standards of the collective wage agreement TV-AVH including further social benefits
The Helmholtz-Zentrum Geesthacht is an equal opportunity employer and particularly strives to increase the percentage of women in the science sector. Severely disabled persons with equal qualifications will be considered preferentially within the framework of legal requirements.
Please send your application indicating job offer
code-no. 2018/WB 4
including your CV, description of your scientific studies and projects, copies of credentials including grades, documentation of your English skills (TOEFL, IELTS or equivalent) and two letters of recommendation, preferably by e-mail in one file not larger than 10 MB to
Closing date for applications is August 16, 2018.