Centre for Biomaterial Development
The research at the Centre for Biomaterial Development in Teltow of the Helmholtz-Zentrum Geesthacht (HZG) is focussed on innovative, polymer-based biomaterials for medical applications. Important topics are synthesis and characterization of stimuli-sensitive polymers and biomimetic materials as well as applications of biomaterials in Regenerative Medicine, especially in the cardiovascular or the musculoskeletal field.
All stages of research are addressed in Teltow, including the design, synthesis, processing, the comprehensive testing for cell tolerance and toxicity, as well as the examination of interactions with physiological environments. The materials, which can be in the form of fibres, films, membranes, particles and porous structures, can be produced both on a laboratory scale and on scales suitable for pre-clinical or clinical tests.
The translation of the results from fundamental research in clinical applications is performed especially at the Berlin-Brandenburg Centre for Regenerative Therapies (BCRT), which is a jointly operated translational research centre of Charité, Universitätsmedizin Berlin and the HZG Centre for Biomaterial Development, whose director Prof. Dr. Andreas Lendlein is also member at the board of directors of BCRT.
At the Centre for the Biomaterial Development, the research and development of high-tech materials can be divided into three main areas:
All stages of research are addressed in Teltow, including the design, synthesis, processing, the comprehensive testing for cell tolerance and toxicity, as well as the examination of interactions with physiological environments. The materials, which can be in the form of fibres, films, membranes, particles and porous structures, can be produced both on a laboratory scale and on scales suitable for pre-clinical or clinical tests.
The translation of the results from fundamental research in clinical applications is performed especially at the Berlin-Brandenburg Centre for Regenerative Therapies (BCRT), which is a jointly operated translational research centre of Charité, Universitätsmedizin Berlin and the HZG Centre for Biomaterial Development, whose director Prof. Dr. Andreas Lendlein is also member at the board of directors of BCRT.
At the Centre for the Biomaterial Development, the research and development of high-tech materials can be divided into three main areas:
- Stimuli-sensitive materials, i.e. material systems that react to an external stimulus such as heat or a magnetic field. That means that they are activated at the request of the user, which is usually the physician. Possible applications are drug-delivery systems.
- Biomimetic material systems based on biopolymers. Typical examples are gelatin-based materials. The resulting materials are used to create biomimetic systems that imitate the structure or function of biological materials.
- Medical-grade copolymers, whose properties are tailored by the combination of different (co)monomers. These (co)monomers can be used in diverse combinations, which is how a wide variety of properties and biofunctionalities are created. The further development of biomaterials requires cell- and tissue specific polymer surfaces – they have to be custom-made for the cells or tissue required. The surface of the copolymers can be used as substrates for cells and varied to achieve good or poor growth of individual cell types.
The Centre for Biomaterial Development has state of the art equipment for synthesis and processing. Cleanrooms and a specially adapted quality management system are assuring quality. Upscaling capacities enable providing materials in the quantities required for clinical studies.
Science
The Research of the Centre for Biomaterial Development is splitted into the following departments:
BCRT / Biointerface Engineering
Innovation management
In the category invation management you find more information to biomaterials, transfer of technology and as well as to topic of quality management.
Furthermore you find there actual informations to our exhibition shows.
Furthermore you find there actual informations to our exhibition shows.
